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Cutaneous sarcoidosis: a dermatologic masquerader.

¹Baylor College of Medicine, Houston, Texas 77030, USA.

American Family Physician

|May 7, 2002

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Cutaneous sarcoidosis, a skin manifestation of a multisystem disease, presents diverse lesions and aids in diagnosis. Systemic glucocorticoids are the primary treatment for severe or widespread skin involvement.

Area of Science:

Dermatology
Immunology
Internal Medicine

Background:

Sarcoidosis is a multisystem inflammatory disease affecting various organs.
Cutaneous sarcoidosis affects up to one-third of patients with systemic sarcoidosis.
Skin lesions offer diagnostic clues and biopsy opportunities.

Purpose of the Study:

To highlight the diverse clinical manifestations of cutaneous sarcoidosis.
To emphasize the diagnostic importance of skin lesions.
To discuss treatment strategies for cutaneous sarcoidosis.

Main Methods:

Review of clinical presentations of cutaneous sarcoidosis.
Histological examination of skin biopsies.
Evaluation of treatment outcomes for skin lesions.

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Main Results:

Cutaneous sarcoidosis exhibits varied morphologies, including papules, plaques, lupus pernio, and scar sarcoidosis.
Rare presentations include alopecia, ulcers, and ichthyosis.
Systemic glucocorticoids are effective for severe or widespread cutaneous disease.

Conclusions:

Cutaneous sarcoidosis is a significant manifestation of sarcoidosis, often presenting as a diagnostic challenge due to its diverse appearances.
Early recognition of skin lesions is crucial for diagnosis and management.
Effective treatment for severe cases involves systemic glucocorticoids.