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A Single Cell Dissociation Approach for Molecular Analysis of Urinary Bladder in the Mouse Following Spinal Cord Injury
Published on: June 17, 2020
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[Clinical study of bladder injury]
Kazuhiro Abe1, Yukihiko Oishi, Syoichi Onodera
1Department of Urology, Tokyo Jikei University School of Medicine.
Hinyokika Kiyo. Acta Urologica Japonica
|May 8, 2002
Summary
Diagnosing bladder injury is challenging due to non-specific symptoms. This study reviewed 15 cases, highlighting diagnostic difficulties and the impact of alcohol intoxication on traumatic bladder injuries.
Area of Science:
- Urology
- Trauma Surgery
- Emergency Medicine
Context:
- Bladder injuries present with non-specific clinical signs, complicating early diagnosis.
- A retrospective review of 15 bladder injury cases (1990-1998) was conducted.
- The study analyzed traumatic and spontaneous bladder injuries.
Purpose:
- To elucidate the clinical characteristics, symptoms, diagnostic methods, and therapeutic approaches for bladder injuries.
- To identify factors contributing to misdiagnosis and delayed treatment.
- To evaluate treatment outcomes and prognosis.
Summary:
- No single clinical symptom reliably indicates bladder injury; gross hematuria was absent in 40% of cases.
- Diagnostic accuracy at initial consultation was low (46.7%), with frequent misdiagnosis as acute abdominal conditions.
- The dome of the bladder was the most common injury site (60%). Alcohol intoxication was a significant factor in traumatic injuries (60%).
- Treatment involved surgical repair (73.3%) or catheterization (26.7%).
Impact:
- Highlights the need for increased clinical suspicion and improved diagnostic strategies for bladder injuries.
- Identifies alcohol intoxication as a key risk factor for traumatic bladder injuries.
- Demonstrates an excellent prognosis with appropriate management, emphasizing timely and accurate diagnosis and treatment.
