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Luminal thrombus disrupts nitric oxide-dependent endothelial physiology
Michael R Davis1, Delio P Ortegon, William D Clouse
1Vascular Surgery, Wilford Hall Medical Center, Lackland Air Force Base, Texas 78236, USA.
The Journal of Surgical Research
|May 22, 2002
Summary
Arterial thrombosis causes acute endothelial dysfunction and reduced nitric oxide (NOx) levels in pigs, without damaging endothelial cells. This large animal model aids in studying vasospasm and thrombolysis.
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