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[Study on biocompatibility of skin reproductive membrane]
1Shanghai Biomaterials Research and Test Center, Shanghai the Second Medical University, Shanghai, P. R. China 200023.
Abstract
Objective:
To study the biocompatibility of skin reproductive membrane.
Methods:
According to ISO's standards, the extractions of the skin reproductive membrane were prepared, and the acute systematic toxicity test, primary skin irritant test, cytotoxicity test, gene expression of type I collagen and fibronectin were detected to evaluate the biocompatibility of skin reproductive membrane.
Results:
All of those tests showed negative results.
Conclusion:
The skin reproductive membrane has excellent biocompatibility in the level of the systematic, cellular and molecular biology.