[Lipid levels in rabbit sarcolemma normally and during experimental muscular dystrophy]

The cholesterin content, total content and phsopholipid composition were studied in sarcolemma of normal rabbits and those with experimental muscular dystrophy. The total content of phospholipids in the sarcolemma of young normal rabbits is 4.8 mg of phosphorus per 1 mg of protein which is higher than that in the sarcolemma of adult rabbits 33%. With experimental muscular dystrophy the content of cholesterin is 2.7 as high as its content in the sarcolemma of the normal rabbits. It is established that the content of phosphatidilserine in the sarcolemma of young normal rabbits is by 61% higher than that in adult animals. The content of phosphatidilserine of lysophosphatidilcholine decreases by 40 and 39%, respectively, with dystrophy. The content of phosphatidilcholine increases by 16% as compared with sarcolemma extracted from the muscles of the young normal rabbits. Molar ratio of phospholipid/cholesterine in the sarcolemma of normal rabbits is 1.8 and decreases with the experimental muscular dystrophy to 0.75.