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Synthesis of histidine2-angiotensin II analogues
Experientia
|November 15, 1975
Abstract:
The synthesis of histidine2-angiotensin II analogues, namely H-Asp-alpha-(im-Bzl)His-Val-Tyr-Ile-(im-Bzl)His-Pro-Phe-OH and H-Asp-beta-(im-Bzl)His-Val-Tyr-Ile-(im-Bzl)His-Pro-Phe-OH, are described. Also a new route leading to the synthesis of alpha-benzyl-L-aspartate, using N-trityl-L-aspartate di-benzyl ester as the starting material, is reported.