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Related Concept Videos

Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...

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Related Experiment Video

Updated: Jul 20, 2026

Surface Electromyographic Biofeedback as a Rehabilitation Tool for Patients with Global Brachial Plexus Injury Receiving Bionic Reconstruction
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Restoration of upper extremity function after peripheral nerve injuries.

D Palencár1, J Janovic, I Hulín

  • 1Department of Plastic Surgery, Medical School of Comenius University, Ruzinov Hospital, Bratislava, Slovakia. palencar@nspr.sk

Acta Chirurgiae Plasticae
|June 11, 2002
PubMed
Summary

Peripheral nerve injuries in the upper extremity are common, requiring knowledge of various reconstruction techniques for effective treatment. This includes immediate/delayed repair, nerve grafting, and muscle/tendon transfers for optimal outcomes.

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Last Updated: Jul 20, 2026

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Area of Science:

  • Orthopedics
  • Neurosurgery
  • Plastic Surgery

Background:

  • Peripheral nerve injuries of the upper extremity are frequent in both domestic and occupational settings.
  • These injuries often involve total or partial nerve lesions, necessitating specialized surgical intervention.

Purpose of the Study:

  • To outline the principles of peripheral nerve reconstruction in the upper extremity.
  • To provide a comprehensive overview of surgical techniques for managing nerve injuries.

Main Methods:

  • Review of established and advanced surgical procedures for peripheral nerve repair.
  • Discussion of techniques including immediate and delayed nerve repair.
  • Exploration of nerve grafting (free and vascularized) and muscle/tendon transfers.

Main Results:

  • Detailed description of various reconstructive methods for upper extremity nerve injuries.
  • Emphasis on the applicability of these techniques for different types of nerve lesions.
  • Highlighting the role of neurotization in functional recovery.

Conclusions:

  • Effective management of upper extremity peripheral nerve injuries relies on a broad understanding of reconstructive principles.
  • A range of surgical options, from nerve grafting to muscle transplantation, are available for restoring function.
  • Multidisciplinary surgical expertise is crucial for successful patient outcomes.