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Updated: Aug 10, 2026

A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients
Published on: August 9, 2022
[Substance migration and health quality of packaged food]
Kazimiera Cwiek-Ludwicka1, Małgorzata Jurkiewicz, Agnieszka Stelmach
1Zakład Badania Zywności i Przedmiotów Uzytku, Państwowy Zakład Higieny, 00-791 Warszawa.
Abstract:
According to legislation the producer is responsible for the product. Products placed on the market must be safe and the relevant documentation confirming the conformity of the product with the accepted limits of global and specific migration must be available from the producer. The provisions concerning acceptable migration limits (global and specific), stimulants and testing methods are set by the relevant regulations. Distilled water, 3% acetic acid, 10% ethanol and olive oil are used as stimulants of foodstuffs. The choice of an appropriate stimulant and testing conditions depends on the type of food expected to come in contact with packaging. According to provisions testing should be performed in the conditions, which possibly closely reflect actual or expected use of the packaging material, taking into account storage of the product as well as possible thermal processing. Test methods for global migration into stimulants using the cell, pouch, by immerse or by article filling are recommended. The criteria used to choose an appropriate testing method are set in European Standards EN 1186. A product meets the quality criteria as set by the legislation if the global migration from the packaging into stimulants does not exceed value of 10 mg/dm2 or 60 mg/kg and if the specific migration limit (SML), set for given substance is not exceeded.
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