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Updated: Aug 17, 2026

Laparoscopic Radical Antegrade Modular Pancreatosplenectomy via Dorsal-Caudal Artery Approach for Pancreatic Neck-Body Cancer
Published on: November 18, 2022
Management of locally advanced adenocarcinoma of the pancreas
David P Ryan1, Christopher G Willett
1Gastrointestinal Cancer Center, Massachusetts General Hospital, Harvard Medical School, Cox 640, 100 Blossom Street, Boston, MA 02114, USA. dpryan@partners.org
Abstract:
Pancreatic cancer is one of the deadliest malignancies and is fatal in more than 95% of affected individuals. For locally advanced disease, the combination of 5-FU and radiation appears to offer the best chance for delaying disease progression. The introduction of gemcitabine into chemoradiotherapy regimens may provide additional improvements in the management of patients. Preoperative therapy has proved feasible but has not shown improvement in overall survival.
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Assessment:

