Bilateral proliferative keratitis in a Domestic Long-haired cat

A 9-year-old, female spayed, Domestic Long-haired cat was presented with bilateral, progressive, pink-white corneal opacities. The referring veterinarian had diagnosed feline herpesvirus-1 (FHV-1) keratitis though diagnostics for FHV-1 had not been performed and treatment with antibiotics and antivirals did not improve the condition. Histopathology showed neutrophils, plasma cells and lymphocytes, but no eosinophils or mast cells. Routine diagnostics did not find an underlying cause, but Southern blot analysis for FHV-1 was positive. The cat responded to topical corticosteroids and cyclosporine when used consistently.