Related Experiment Video
Updated: Aug 11, 2026

09:35
Neurodevelopmental Reflex Testing in Neonatal Rat Pups
Published on: April 24, 2017
Breed-Specific Relationship Between Rebound Tonometers (TonoVet and TonoVet Plus) in Labrador Retrievers
1Laboratory of Veterinary Surgery, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Tokyo, Japan.
Veterinary Ophthalmology
|August 9, 2026
Summary
The TonoVet Plus consistently measures higher intraocular pressure (IOP) than the TonoVet in Labrador retrievers. A new approximation aids longitudinal IOP tracking after device changes.
Area of Science:
- Veterinary Ophthalmology
- Ophthalmic Diagnostics
Background:
- Intraocular pressure (IOP) is a critical metric in canine eye health.
- Rebound tonometry is commonly used for IOP measurement in dogs.
- Replacing tonometers necessitates understanding measurement differences for consistent monitoring.
Purpose of the Study:
- To compare intraocular pressure (IOP) readings between TonoVet and TonoVet Plus rebound tonometers in Labrador retrievers.
- To develop a regression-based approximation to bridge IOP data following device replacement.
Main Methods:
- Fifty-three clinically normal Labrador retrievers were included.
- Intraocular pressure (IOP) was measured sequentially with TonoVet and TonoVet Plus.
- Paired t-tests, correlation, Bland-Altman analysis, and Deming regression were employed.
Main Results:
- TonoVet Plus showed significantly higher IOP readings than TonoVet (mean difference +4.5 mmHg).
- A moderate positive correlation (r=0.69) was found between devices.
- Deming regression provided an approximation (slope=1.05, intercept=3.52).
Conclusions:
- TonoVet Plus systematically overestimates IOP compared to TonoVet in Labrador retrievers.
- The derived approximation may aid longitudinal IOP interpretation but requires external validation.

