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Brevibacterium endocarditis: a first report.

Krishna N Dass1, Margo A Smith, Vee J Gill

  • 1Infectious Disease Service, Washington Hospital Center, Washington, DC 20010, USA. Krishna.Dass@medstar.net

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|June 28, 2002
PubMed
Summary
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This study reports the first case of Brevibacterium endocarditis, a rare heart valve infection caused by Brevibacterium otitidis. The patient with prosthetic heart valves successfully responded to antibiotic treatment.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Brevibacterium species are rarely associated with human infections.
  • Endocarditis is a serious infection of the heart lining or valves.
  • No previous cases of endocarditis caused by Brevibacterium have been documented.

Observation:

  • A patient with prosthetic heart valves developed an infection.
  • The infection was identified as endocarditis caused by Brevibacterium otitidis.

Findings:

  • This is the first reported case of Brevibacterium endocarditis.
  • The patient received a 6-week course of vancomycin and a 2-week course of gentamicin.
  • Long-term maintenance therapy with oral azithromycin was initiated.

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Implications:

  • Highlights Brevibacterium otitidis as a potential pathogen in endocarditis.
  • Demonstrates successful treatment strategies for this rare infection.
  • Informs clinical management of prosthetic valve endocarditis.