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Clinical experience with specific immunotherapy to horse dander.
Laureano Fernández-Távora1, Pilar Rico, Santiago Martín
1Ambulatorio Virgen de la Cinta, Huelva, Spain. laureano2000@terra.es
Summary
Specific immunotherapy using horse dander extract is safe and effective for treating horse allergies. Patients experienced significant symptom reduction and high satisfaction with this allergy treatment.
Area of Science:
- Allergy and Immunology
- Immunotherapy Research
- Clinical Trials
Background:
- Horse dander allergy affects many individuals, causing significant cutaneous and respiratory symptoms.
- Specific immunotherapy (SIT) offers a potential treatment for allergic diseases.
Purpose of the Study:
- To evaluate adverse reactions during specific immunotherapy (SIT) with horse dander.
- To assess the efficacy of SIT in improving horse-induced allergic symptoms.
Main Methods:
- An open clinical study involving 24 patients with horse-induced allergy.
- Standardized horse dander extract (Alutard SQ) was administered.
- Adverse reactions and symptom changes were monitored.
Main Results:
- Mild local and systemic reactions occurred during dose induction, with good tolerance after dose adjustment.
- Significant reductions in conjunctivitis (100%), rhinitis (93%), asthma (90%), and skin symptoms (87%) were observed.
- 95% of patients reported high satisfaction with the treatment's efficacy and suitability.
Conclusions:
- Specific immunotherapy with standardized horse allergen extract is a safe treatment option.
- SIT demonstrates beneficial effects for patients with moderate to severe allergic rhinoconjunctivitis and/or asthma.