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Enflurane (ethrane)-a preliminary study in children.

K D Alexander, W H Cole, J H Havill

    Anaesthesia and Intensive Care
    |November 1, 1975
    PubMed
    Summary
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    Enflurane is a safe and effective inhalational anesthetic for pediatric patients. Clinical trials confirm its satisfactory use without significant adverse events in children.

    Area of Science:

    • Anesthesiology
    • Pediatric Medicine
    • Pharmacology

    Background:

    • Inhalational anesthetics are crucial for pediatric surgical procedures.
    • Evaluating the safety and efficacy of anesthetic agents in children is essential.
    • Enflurane has been used in adult anesthesia, but its pediatric application requires specific investigation.

    Purpose of the Study:

    • To assess the efficacy of enflurane as an inhalational anesthetic in pediatric patients.
    • To determine the safety profile and identify any serious adverse effects associated with enflurane use in children.

    Main Methods:

    • A clinical trial was conducted involving pediatric patients requiring anesthesia.
    • Enflurane was administered as the primary inhalational anesthetic agent.

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  • Patient outcomes, including anesthetic effectiveness and adverse events, were monitored and recorded.

    • Main Results:

    • Enflurane demonstrated satisfactory anesthetic properties in the pediatric patient group.
    • No serious adverse effects were reported during the administration of enflurane.
    • The agent proved to be a reliable option for pediatric anesthesia.

    Conclusions:

    • Enflurane is confirmed as a suitable inhalational anesthetic for pediatric use.
    • The study supports the use of enflurane in children due to its favorable safety and efficacy profile.
    • Further research may explore long-term outcomes, but initial findings are promising.