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Hydroxy-substituted oligopyridine dicarboxamide helical foldamers
Ivan Huc1, Victor Maurizot, Heinz Gornitzka
1Institut Européen de Chimie et Biologie, 16 av. Pey Berland, 33607 Pessac, France. i.huc@iecb-polytechnique.u-bordeaux.fr
Chemical Communications (Cambridge, England)
|July 18, 2002
Abstract:
As shown by X-ray diffraction and NMR studies, short oligopyridine dicarboxamides bearing benzyloxy, hydroxy and hydroxylate moieties adopt very robust single helical conformations, even in water.