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Updated: Aug 15, 2026

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
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Hollow nanoparticles via stepwise complexation and selective decomplexation of poly(ethylene imine)

Sascha General1, Jan Rudloff, Andreas F Thünemann

  • 1Max Planck Institute of Colloids and Interfaces, Research Campus Golm, D-14424 Potsdam-Golm, Germany.

Chemical Communications (Cambridge, England)
|July 18, 2002
PubMed

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Complexation Equilibria: The Chelate Effect01:19

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In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...