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Tandem intermolecular Suzuki coupling/intramolecular vinyl triflate-arene coupling
Michael C Willis1, Christelle K Claverie, Mary F Mahon
1Department of Chemistry, University of Bath, Bath, UK BA2 7AY. m.c.willis@bath.ac.uk
Chemical Communications (Cambridge, England)
|July 19, 2002
Abstract:
Treatment of a benzyl substituted meso-ditriflate with boronic acids in the presence of palladium acetate, triphenylphosphine and caesium fluoride results in intermolecular Suzuki coupling followed by vinyl triflate-arene cyclisation to provide, in high yields, single regioisomers of tricyclic-carbocycles.