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Cadherins communicate structural plasticity of presynaptic and postsynaptic terminals
1MRC Cell Biology Unit and Laboratory for Molecular Cell Biology, University College London, Gower Street, United Kingdom.
Neuron
|July 19, 2002
Abstract:
Synapse adhesion molecules play a key role in specifying and facilitating the recognition of axodendritic contacts. New studies by and reported in this issue of Neuron reveal multiple functions for the cadherin-catenin complex. This adhesion complex regulates synaptogenesis and coordinates synaptic strength with presynaptic and postsynaptic organization, including the shape of dendritic spines.