Related Experiment Videos
Labelling of [Leu5]-enkephalin with organometallic Mo complexes by solid-phase synthesis
Dave R van Staveren1, Nils Metzler-Nolte
1Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470 Mülheim/Ruhr, Germany.
Chemical Communications (Cambridge, England)
|July 20, 2002
Abstract:
The neuropeptide leucine-enkephalin ([Leu5]-enkephalin) has been covalently labelled with the two organometallic Mo carbonyl complexes Mo(R-His)(allyl)(CO)2 (His = N delta,N,O-L-histidinate) and Mo(R-bpa)(CO)3 (bpa = bis(2-picolyl)a-mine) on the resin as the last step of a solid-phase synthesis scheme and in solution.