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Successful pregnancy in a patient with a 46,XY karyotype
Kamala Selvaraj1, Vijaya Ganesh, Priya Selvaraj
1Fertility Research Center, G.G. Hospital, Tamil Nadu, India. kamala@giasmd01.vsnl.net.in
Objective:
To report a case of successful pregnancy in a patient with 46,XY karyotype with primary ovarian failure.
Design:
Case report.
Setting:
Fertility Research Center, G.G. Hospital, Chennai, Tamil Nadu, India.
Patient(S):
A 27-year-old woman with hypoplastic uterus, normal fallopian tubes on both sides, and gonadal dysgenesis.
Intervention(S):
Chromosomal analysis, diagnostic laparoscopy, donor oocyte program, gamete intrafallopian transfer, and gonadectomy.
Main Outcome Measure(S):
Response to hormone replacement therapy and the probability of achieving a pregnancy by a tubal procedure.
Result(S):
Treatment was successful, and the patient delivered a live baby.
Conclusion(S):
A hypoplastic uterus of patients with the 46,XY karyotype can be stimulated by the use of cyclical steroid therapy to accommodate pregnancy and facilitate tubal procedures in patients with normal fallopian tubes.