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Updated: Dec 17, 2025

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Published on: May 17, 2024
A Rare Case Report of Sirenomelia Following Intracytoplasmic Sperm Injection Embryo Transfer
Kamala Selvaraj1, Priya Selvaraj1, S Sivapriya1
1GG Hospital, Fertility Research and Women's Speciality Centre, Chennai, Tamil Nadu, India.
Abstract:
Sirenomelia is a very rare developmental abnormality which is characterized by fusion of lower limb to form a single limb. This condition is often associated with internal organ abnormality and is considered incompatible with life. Sirenomelia is sporadically reported from across the world, but no case associated with artificial reproductive technology (ART) has not been reported. We report a case of sirenomelia in a 29-year old woman who conceived by ART, which to our knowledge is the first reported case in ART. The defect was detected early during first trimester and the pregnancy was terminated.
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