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[Characterization of antilysozyme and anticomplement signs in brucellae during experimental infection]
N V Sheenkov1, A G Iakovlev, M V Skachkov
1Regional Center of State Sanitary and Epidemiological Surveillance, Institute of Cellular and Intracellular Symbiosis, State Medical Academy, Research and Production Veterinary Laboratory, Municipal Clinical Infectious Hospital, Orenburg, Russia.
Zhurnal Mikrobiologii, Epidemiologii I Immunobiologii
|July 27, 2002
Abstract:
The dependence of the course of experimental infection on the initial level of antilysozyme activity of Brucella clones was studied using 40 noninbred guinea pigs. As revealed in this study, the antilysozyme sign of brucellae influenced the pathogenesis of brucellosis, facilitating the prolonged survival of brucellae in the host body. The results thus obtained may be used for the prognostication of the course of Brucella infection.