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Related Experiment Videos

Osteoporosis in men.

Neil Binkley1, Diane Krueger

  • 1Osteoporosis Clinical Center and Research Program and Institute on Aging, University of Wisconsin-Madison, USA. nbinkley@facstaff.wisc.edu

WMJ : Official Publication of the State Medical Society of Wisconsin
|August 3, 2002
PubMed
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Osteoporosis affects 1 in 4 men, causing more severe fractures. Early diagnosis and treatment are crucial for men

Area of Science:

  • Endocrinology
  • Geriatrics
  • Orthopedics

Background:

  • Osteoporosis is often perceived as a women's disease, but men face significant fracture risks.
  • Lifetime fracture risk in men is 1 in 4, with males accounting for 30% of hip fractures.
  • Men experience higher morbidity and mortality from osteoporotic fractures compared to women.

Purpose of the Study:

  • To highlight the current understanding of osteoporosis in men.
  • To review epidemiology, pathophysiology, diagnosis, and treatment of male osteoporosis.
  • To emphasize the need for increased attention to osteoporosis in men.

Main Methods:

  • Review of current literature on male osteoporosis.
  • Discussion of recently published indications for bone mass measurement in men.

Related Experiment Videos

  • Analysis of secondary causes of bone loss and laboratory evaluation in osteoporotic men.
  • Main Results:

    • Indications for bone mass measurement in men include hypogonadism and corticosteroid use.
    • A consensus diagnosis of osteoporosis at a T-score of -2.5 or below is forthcoming.
    • Secondary causes of bone loss are found in up to two-thirds of osteoporotic men, including corticosteroid use, alcohol abuse, hypogonadism, and idiopathic hypercalciuria.

    Conclusions:

    • Osteoporosis is a significant health concern for men, with substantial fracture risk and worse outcomes.
    • Laboratory evaluation is indicated for osteoporotic men to identify secondary causes of bone loss.
    • Pharmacologic treatments for osteoporosis are now approved for men, improving management options.