[Effect of Triton-100 on activity and solubilization of brain acid proteinases]

The activity and solubilization of acid proteinases of grey and white matter of the cat great cerebral hemispheres were studied as affected by the detergent triton X-100. High concentrations of the detergent evoke a significant decrease of the activity in grey matter and significant increase--in white one. It is found that 20-25% of the activity of the grey matter acid proteinases are strongly bound with the studied tissues and not release under the effect of the detergent in high concentrations.