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Electroconvulsive therapy in treatment-resistant mania: case reports.
Marcia Britto de Macedo Soares1, Ricardo Alberto Moreno, Doris Hupfeld Moreno
1Mood Disorders Unit (GRUDA), Psiquiatric Institute, Hospital das Clínicas, Faculty of Medicine, University of São Paulo.
Revista Do Hospital Das Clinicas
|August 10, 2002
Summary
Electroconvulsive therapy (ECT) shows promise for treating treatment-resistant mania in bipolar disorder. Initial results indicate a satisfactory response, warranting further investigation into ECT
Area of Science:
- Psychiatry
- Neurology
Background:
- Electroconvulsive therapy (ECT) is an established treatment for mood disorders.
- Limited prospective studies exist on ECT for treatment-resistant manic episodes.
Observation:
- Three treatment-resistant bipolar patients meeting DSM-IV criteria for mania were included.
- Patients received 12 bilateral ECT sessions.
- Weekly assessments used validated scales: Young Mania Rating Scale, Hamilton Rating Scale for Depression, Brief Psychiatric Rating Scale, and Clinical Global Impressions-Bipolar Version.
Findings:
- All three patients demonstrated a satisfactory response to ECT.
- Variations in the response trajectory were noted among the patients.
Implications:
- ECT may be a viable option for managing treatment-resistant bipolar mania.
- Further research is recommended to confirm ECT's efficacy in this patient population.