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Related Experiment Videos

Update on anorexia and cachexia.

Florian Strasser1, Eduardo D Bruera

  • 1Department of Palliative Care and Rehabilitation Medicine, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Box 0008, Houston, TX 77030, USA.

Hematology/Oncology Clinics of North America
|August 13, 2002
PubMed
Summary
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Anorexia and cachexia in advanced cancer significantly impair patient function but are no longer unavoidable. Early screening, comprehensive assessment, and multimodal therapy, including nutrition and pharmacologic options, are key to managing these debilitating symptoms.

Area of Science:

  • Oncology
  • Palliative Care
  • Clinical Nutrition

Background:

  • Anorexia and cachexia significantly reduce physical, emotional, and social function in advanced cancer patients.
  • These symptoms cause considerable distress for patients and their families, impairing quality of life.
  • The decline associated with cancer anorexia and cachexia is not an unavoidable consequence and can be managed.

Purpose of the Study:

  • To highlight the necessity of routine screening and comprehensive assessment for anorexia and cachexia.
  • To outline treatment strategies prioritizing physical, psychosocial, and existential needs.
  • To emphasize the need for multimodal and interdisciplinary therapeutic approaches.

Main Methods:

  • Routine screening and careful, comprehensive assessment for anorexia and cachexia.

Related Experiment Videos

  • Prioritization of concurrent physical, psychosocial, and existential problems in treatment decisions.
  • Identification and treatment of reversible causes of anorexia and cachexia.
  • Consideration of nutritional interventions, pharmacologic therapies, and palliative care.

    • Main Results:

    • Early identification and intervention can mitigate the decline in function associated with anorexia and cachexia.
    • Nutritional interventions are beneficial, particularly for patients with starvation components.
    • Pharmacologic therapies (corticosteroids, progestins, prokinetics) may be indicated, with new treatments anticipated.
    • Multimodal and interdisciplinary therapy is required for this complex syndrome.

    Conclusions:

    • Anorexia and cachexia are manageable conditions in advanced cancer, not an inevitable decline.
    • A proactive, integrated approach involving screening, assessment, and tailored therapies is essential.
    • Specialist palliative care plays a crucial role in managing symptoms and supporting patients and families.