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[Carcinoma developing in extragonadal endometriosis--analysis of two cases]
Grzegorz Panek1, Jan Zieliński
1Kliniki Nowotworów Narzadów Płciowych Kobiecych Centrum Onkologii Instytutu w Warszawie.
Ginekologia Polska
|August 21, 2002
Abstract:
Two cases of invasive carcinoma developing in extragonadal endometriosis are presented. Each case had a different clinical course. In addition to routine histopathologic studies immunohistochemical studies to assess the expression of cytoceratin and glycoprotein CD-44 were performed. In both cases CK-7 expression was higher in malignancy then in the endometrioid tissue. Very high expression of CD-44 protein (marker of metastatic potential) was found in patients with poor progress of the disease.