[Antioxidant system in rat tissues in hypothermia and dalargin introduction]

S P L'vova¹, E M Abaeva, A G Gasangadzhieva

¹Research Institute of Biology, Dagestan State University, Dagestan, Makhachkala, 367025, ul. M. Gadzhieva 43a.

Voprosy Meditsinskoi Khimii

|August 23, 2002

Abstract:

Total antioxidative activity, activity of water soluble fraction of antioxidative system, superoxide dismutase and catalase activities in brain, liver, myocard, skeletal muscle, kidney and serum at hypothermia 30 degrees C, 20 degrees C and self-warming from 20 degrees C to 37 degrees C were studied. Activity of antioxidative system is sustained at high level, except superoxide dismutase. The latter is activated significantly at 30 degrees C hypothermia prolonged up to 3 h. Dalargin injection 30 min before onset of cooling stabilizes the erythrocyte membrane without enhancement of antioxidative activity in majority of investigated tissues.

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Abstract:

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