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Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid
Tomasz Laskus1, Marek Radkowski, Agnieszka Bednarska
1Division of Transplantation Medicine, Mayo Clinic, Scottsdale, Arizona 85259, USA.
Journal of Virology
|September 5, 2002
Abstract:
Hepatitis C virus (HCV) sequences were detected in cerebrospinal fluid (CSF) in 8 of 13 HCV-positive patients. In four patients harboring different virus strains in serum and peripheral blood mononuclear cells (PBMC), CSF-derived virus was similar to that found in PBMC, which suggests that PBMC could carry HCV into the brain.