Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

New fluorocarbon iodides.

R D Chambers1, J A Cooper, E Copin

  • 1University of Durham, Department of Chemistry, South Road, Durham, UK DH1 3LE. R.D.Chambers@durham.ac.uk

Chemical Communications (Cambridge, England)
|September 21, 2002
PubMed
Summary

Researchers developed a new, efficient method to synthesize fluorocarbon iodides and di-iodides. These compounds were then successfully used in reactions with thiols, showing their synthetic versatility.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multiband reflectometry system for density profile measurement with high temporal resolution on JET tokamak.

The Review of scientific instruments·2010
Same author

Elemental fluorine. Part 13. Gas-liquid thin film microreactors for selective direct fluorination.

Lab on a chip·2004
Same author

Nucleophilic substitution and Claisen rearrangement reactions of model fluoroalkenes of general structure R-CF=CF-CF3.

The Journal of organic chemistry·2001
Same author

Protection from lethal murine graft-versus-host disease without compromise of alloengraftment using transgenic donor T cells expressing a thymidine kinase suicide gene.

Blood·2001
Same author

Vertebrate isoforms of actin capping protein beta have distinct functions In vivo.

The Journal of cell biology·1999
Same author

Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation.

Neuron·1999

Area of Science:

  • Organic Chemistry
  • Fluorine Chemistry
  • Synthetic Chemistry

Background:

  • Fluorocarbon compounds are valuable in various chemical applications.
  • Efficient synthesis of functionalized fluorocarbons remains an active area of research.
  • Incorporating hydrocarbon groups offers tunable properties.

Purpose of the Study:

  • To develop a general and efficient synthetic route for fluorocarbon iodides and di-iodides with hydrocarbon substituents.
  • To demonstrate the synthetic utility of these novel fluorocarbon compounds.

Main Methods:

  • A novel synthetic strategy was employed for the preparation of fluorocarbon iodides and di-iodides.
  • The synthesized compounds were characterized using standard analytical techniques.
  • Reactions with thiols were performed to evaluate their synthetic applicability.

Main Results:

  • A general and efficient method for synthesizing fluorocarbon iodides and di-iodides bearing hydrocarbon groups was established.
  • The successful reaction of these compounds with thiols was demonstrated.
  • The study provides new building blocks for fluorocarbon chemistry.

Conclusions:

  • The developed synthetic approach is effective for accessing diverse fluorocarbon iodides.
  • The demonstrated reactivity with thiols highlights the potential of these compounds in further synthetic transformations.
  • This work expands the toolkit for creating complex fluorinated molecules.

Related Experiment Videos