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Exercise-induced asthma.

Kai-Håkon Carlsen1, Karin C L Carlsen

  • 1Voksentoppen National Hospital and Research Institute of Asthma, Allergy and Chronic Lung Diseases in Children, Voksentoppen, Ullveien 14, Oslo, Norway.

Paediatric Respiratory Reviews
|September 26, 2002
PubMed
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Exercise-induced asthma (EIA) in children and adolescents significantly impacts daily life. Effective management involves standardized exercise tests for diagnosis and treatments like inhaled steroids and beta(2)-agonists.

Area of Science:

  • Pediatric Pulmonology
  • Exercise Physiology

Background:

  • Exercise-induced asthma (EIA) is prevalent in pediatric asthma patients, affecting up to 30% of individuals.
  • EIA involves bronchoconstriction post-exercise due to respiratory water/heat loss and mediator release.
  • Managing EIA is crucial for maintaining daily activities in asthmatic children and adolescents.

Purpose of the Study:

  • To outline diagnostic methods for EIA.
  • To review effective treatment strategies for EIA.
  • To assess the impact of physical training on EIA.

Main Methods:

  • Standardized exercise testing, including treadmill running at 95% maximum load for 6-8 minutes.
  • Utilizing cold air inhalation to enhance diagnostic test sensitivity.
  • Reviewing pharmacological interventions and physical training regimens.

Related Experiment Videos

Main Results:

  • Diagnosis is best confirmed via standardized exercise tests, with cold air inhalation improving sensitivity.
  • Optimal treatment includes inhaled corticosteroids combined with pre-exercise beta(2)-agonists and/or leukotriene antagonists.
  • Physical training enhances fitness and quality of life but does not improve lung function or bronchial responsiveness.

Conclusions:

  • Standardized exercise tests are key for EIA diagnosis in children.
  • A combination of inhaled steroids and pre-exercise medication is the most effective treatment approach.
  • While beneficial for overall well-being, physical training does not alter the underlying pathophysiology of EIA.