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An efficient synthesis of endo,exo-furofuranone derivatives
Nigel A Swain1, Richard C D Brown, Gordon Bruton
1Department of Chemistry, University of Southampton, Southampton, UK SO17 1BJ.
Abstract:
The ring openings of 1-acetyl-4-phenyl-3-oxabicyclo[3.1.0]hexane afforded alpha-acetyl-gamma-butyrolactone that underwent a novel diazo-transfer reaction, followed by C-H insertion, to provide a series of endo,exo-furofuranone analogues.