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Studies on the biomimetic synthesis of SNF4435 C and D
John E Moses1, Jack E Baldwin, Rodolfo Marquez
1Chemical Crystallography, Oxford University, South Parks Road, Oxford OX1 3QR, U.K.
Organic Letters
|October 12, 2002
Abstract:
[reaction: see text] The biomimetic synthesis of the bicyclic core of the novel immunosuppresants SNF4435C and SNF4435D is reported. The core framework was efficiently generated from the all-trans tetraene precursor in one step and in good yield.