Related Experiment Video
Updated: Sep 9, 2026

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
Use of prehospital fluids in hypotensive blunt trauma patients
David J Dula1, G Craig Wood, Abbey R Rejmer
1Department of Emergency Medicine, Geisinger Medical Center, Danville, PA 17822, USA. ddula@geisinger.edu
Objective:
To compare the outcomes of blunt trauma victims with systolic blood pressure < or = 90 mm Hg who received prehospital fluids with the outcomes of those who did not receive prehospital fluids.
Methods:
This matched-pairs case-control study used records of blunt trauma patients with scene systolic blood pressure < or = 90 mm Hg obtained from the Pennsylvania Trauma Systems Foundation. Patients who received > 500 mL prehospital fluids (n = 75) were matched by Injury Severity Score (ISS) and systolic blood pressure on scene with those who did not receive any prehospital fluids (n = 75). Outcomes compared included change in systolic blood pressure, survival to discharge, and length of hospital stay.
Results:
Those who received fluids were more likely to have an increase in systolic blood pressure at arrival to the emergency department [odds ratio for fluid use = 2.41; 95% confidence interval (95% CI) = 1.02, 5.73; p = 0.046]. There was no significant difference in survival to discharge (odds ratio for fluid use = 1.02; 95% CI = 0.40, 2.60; p = 0.969). There was no significant difference in length of hospital stay: 5.4 days (SD = 2.8) for those with fluids; 5.2 days (SD = 2.8) for those with no fluids; difference = 0.2 days; 95% CI = -1.6, 1.8; p = 0.870.
Conclusions:
This study suggests that prehospital fluid resuscitation of blunt injured trauma patients with systolic blood pressure < or = 90 increases systolic blood pressure but has no effect on survival or length of hospital stay.
Related Concept Videos
Blood Pressure Imbalances and Circulatory Shock
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
Flail Chest-II
Assessment:
1. Clinical Evaluation:
History:
Cardiopulmonary Resuscitation IV: Pharmacological Management

