Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vulvar cancer.

Timothy P Canavan1, Donna Cohen

  • 1Department of Family and Community Medicine, Lancaster General Hospital, Pennsylvania, USA.

American Family Physician
|October 22, 2002
PubMed
Summary
This summary is machine-generated.

Vulvar cancer presents as two distinct diseases, one linked to human papillomavirus in younger women and another to chronic inflammation in older women. Early detection through biopsy is crucial for effective treatment and managing its impact on sexuality.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Obesity in Pregnancy: Updates and Considerations.

American family physician·2026
Same author

Hormone Therapy for Sexual Function in Postmenopausal Women.

American family physician·2024
Same author

Medical Methods for First-Trimester Abortion.

American family physician·2023
Same author

Effect of Psychotherapy on Patients With Borderline Personality Disorder.

American family physician·2022
Same author

Reducing pelvic floor injury by induction of labor.

International urogynecology journal·2022
Same author

A Pilot of a Randomized Control Trial of Melatonin and Vitamin C for Mild-to-Moderate COVID-19.

Journal of the American Board of Family Medicine : JABFM·2022
Same journal

For Post-stent Patients With Atherosclerotic Coronary Vascular Disease Who Are Taking an Anticoagulant, Adding Aspirin Worsens Outcomes.

American family physician·2026
Same journal

Nausea and Vomiting During Pregnancy.

American family physician·2026
Same journal

Metabolic Dysfunction-Associated Steatotic Liver Disease: Diagnosis and Management.

American family physician·2026
Same journal

Aerobic Exercise Is the Better Exercise Modality for Knee Osteoarthritis.

American family physician·2026
Same journal

Overscreening Leads to Overdiagnosis of MASLD.

American family physician·2026
Same journal

Type 2 Diabetes: Outpatient Insulin Management.

American family physician·2026
See all related articles

Area of Science:

  • Gynecologic Oncology
  • Dermatology
  • Pathology

Background:

  • Vulvar cancer, though uncommon, necessitates early detection due to its impact on sexuality.
  • Recent evidence suggests vulvar cancer comprises two distinct disease entities.
  • One type is associated with human papillomavirus (HPV) and vulvar intraepithelial neoplasia, increasing in young women.
  • The second type, prevalent in older women, may arise from chronic inflammation and vulvar non-neoplastic epithelial disorders.

Purpose of the Study:

  • To review the current understanding of vulvar cancer etiology, diagnosis, and management.
  • To highlight the importance of differentiating between the two proposed types of vulvar cancer.
  • To emphasize timely diagnosis and treatment strategies.

Main Methods:

Related Experiment Videos

  • Histological diagnosis is the gold standard for vulvar cancer.
  • Biopsy (excisional or punch) of suspicious vulvar lesions is essential.
  • Clinical monitoring of suspicious lesions is critical due to common delays in diagnosis.
  • Staging utilizes the TNM classification system.

Main Results:

  • Vulvar cancer incidence was 3,200 cases in 1998, with 800 deaths.
  • Two distinct pathways for vulvar cancer development are proposed.
  • HPV-related vulvar cancer is increasing in younger populations.
  • Chronic inflammation-related vulvar cancer affects older women.

Conclusions:

  • Accurate histological diagnosis via biopsy is paramount for vulvar cancer.
  • Prompt management is crucial to improve patient outcomes and minimize psychosexual complications.
  • A trend towards conservative surgical approaches aims to reduce treatment-related morbidity.