Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tick paralysis: electrophysiologic studies.

T R Swift, O J Ignacio

    Neurology
    |December 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Tick paralysis in a patient was studied using nerve conduction tests. Removing the tick reversed nerve conduction abnormalities, improving muscle action potentials and nerve signal speed.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Development of trochlear motor neurons, superior oblique muscle, and neuromuscular junctions following prevention of cell death by myasthenia gravis immunoglobulin.

    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience·2014
    Same author

    Chronic spinal cord transection does not affect peripheral nerve regeneration.

    Restorative neurology and neuroscience·2011
    Same author

    The US health care system: Part 1: Our current system.

    Neurology·2008
    Same author

    Invited article: the US health care system: part 2: proposals for improvement and comparison to other systems.

    Neurology·2008
    Same author

    Asystole induced by edrophonium following beta blockade.

    Neurology·2001
    Same author

    Influence of age and height on nerve conduction.

    Muscle & nerve·2001
    Same journal

    Factors Associated With Disability Improvement and Worsening Independent of Attacks in Patients With AQP4-IgG+ NMOSD and MOGAD: A Multicenter Cohort Study.

    Neurology·2026
    Same journal

    Cost-Effectiveness of Intracranial Aneurysm Screening: A Systematic Review.

    Neurology·2026
    Same journal

    Rare Eating Epilepsy: Co-Occurrence of Focal Cortical Dysplasia and Gray Matter Heterotopia.

    Neurology·2026
    Same journal

    Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

    Neurology·2026
    Same journal

    Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome.

    Neurology·2026
    Same journal

    At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease.

    Neurology·2026
    See all related articles

    Area of Science:

    • Neurology
    • Toxicology

    Background:

    • Tick paralysis is a rare neurological disorder caused by toxins secreted by certain ticks.
    • Nerve conduction studies (NCS) are crucial for diagnosing peripheral neuropathies.

    Observation:

    • A patient with tick paralysis underwent serial NCS before and after engorged tick removal.
    • Pre-removal NCS showed reduced motor action potential amplitudes and prolonged latencies.
    • Post-removal NCS demonstrated rapid improvement in amplitudes and latencies.

    Findings:

    • Nerve conduction velocities improved significantly 6 months post-tick removal.
    • Direct muscle stimulation yielded normal responses, ruling out primary muscle pathology.
    • Neuromuscular junction transmission tests, including response to edrophonium, were normal.

    Related Experiment Videos

    Implications:

    • These findings suggest tick toxins primarily affect motor nerve terminals and large nerve fibers.
    • NCS can effectively monitor recovery from tick paralysis.
    • The study supports experimental data on the neurotoxic effects of tick saliva.