[Adult progeria (Werner's syndrome)]

Two cases of Progeria of the adult (Werner's Syndrome) are presented. The outstanding characteristic of the mentioned syndrome is an early, progressive and fatal aging of the patient. The study of those two cases suggested, first: a literature search which has shown 140 references to the Werner's Syndrome up to 1971, and second: a clinical features review about general manifestations and specific particularities concerning the skin, cardiovascular system, eyes, glandular system, laboratory tests, etc. Our two patients, who respond to the signs required by Thannhauser for the diagnosis of the Werner's Syndrome, were very useful to clarify the clinical features review undestalren.