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Furcation therapy with bioabsorbable collagen membrane: a clinical trial
Vijay K Pruthi1, Shirley C Gelskey, Sayed M Mirbod
1Department of Dental Diagnostic and Surgical Sciences, Faculty of Dentistry, University of Manitoba, Winnipeg, Manitoba, Canada. pruthi@ms.umanitoba.ca
Journal (Canadian Dental Association)
|November 2, 2002
Summary
This study found collagen membranes offer similar or better results than expanded polytetrafluoroethylene (e-PTFE) membranes for treating Class II furcation defects. Collagen showed a significant advantage in vertical fill for mandibular molars.
Area of Science:
- Periodontology
- Regenerative Dentistry
- Biomaterials Science
Background:
- Class II furcation defects in mandibular molars present a significant clinical challenge.
- Barrier membranes, including expanded polytetrafluoroethylene (e-PTFE) and collagen, are used in regenerative periodontal therapy.
- Comparing the efficacy of different barrier membranes is crucial for optimizing treatment outcomes.
Purpose of the Study:
- To compare the effectiveness of expanded polytetrafluoroethylene (e-PTFE) and collagen barrier membranes in treating human Class II furcation defects.
- To evaluate soft-tissue and hard-tissue regeneration following treatment with e-PTFE versus collagen membranes.
- To determine which membrane material yields superior clinical attachment gain and defect fill.
Main Methods:
- A comparative study involving 17 non-smoking subjects with Class II furcation defects in mandibular molars.
- Initial periodontal therapy followed by surgical placement of either e-PTFE or collagen membranes, covered by a coronally positioned flap.
- Soft-tissue measurements (gingival index, probing depth, recession, clinical attachment level) at 8-month follow-up and hard-tissue measurements (horizontal probing depth, vertical fill) at 12-month re-entry.
Main Results:
- No statistically significant differences were observed between e-PTFE and collagen membranes regarding gingival index, probing depth reduction, or clinical attachment gain.
- Both membranes demonstrated effective management of horizontal defect fill.
- A statistically significant improvement in vertical fill was noted with the collagen membrane compared to the e-PTFE membrane (p < 0.05).
Conclusions:
- Collagen membranes demonstrate comparable efficacy to e-PTFE membranes in treating Class II furcation defects, with similar improvements in most periodontal parameters.
- Collagen membranes may offer a superior outcome in terms of vertical bone fill in Class II furcation defects.
- Collagen appears to be a beneficial material for regenerative therapy of furcation defects, potentially outperforming e-PTFE in specific regenerative aspects.