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Malignant transformation in odontogenic keratocysts. Case report
1Catedra de Anatomia Patologica Facultad de Odontologia U.B.A. Marcelo T. Alvear 2142, Sector A C1122 AAH Buenos Aires, Argentina. akeszler@hotmail.com
Medicina Oral : Organo Oficial De La Sociedad Espanola De Medicina Oral Y De La Academia Iberoamericana De Patologia Y Medicina Bucal
|November 5, 2002
Summary
Squamous cell carcinoma rarely develops in odontogenic keratocysts, with only 12 previous cases documented. This report details a new case in a 70-year-old male, including diagnostic and treatment information.
Area of Science:
- Oral pathology
- Oncology
- Dental medicine
Background:
- Odontogenic keratocysts (OKCs) are common developmental cysts of the jaw.
- Malignant transformation within an OKC is exceptionally rare.
- Squamous cell carcinoma (SCC) is the most common malignancy associated with odontogenic cysts.
Observation:
- A new case of SCC arising in the epithelial lining of an OKC is presented.
- The patient was a 70-year-old male.
- Clinical, radiographic, and histopathological data were collected.
Findings:
- Histopathological examination confirmed the diagnosis of SCC within the OKC.
- The tumor exhibited characteristic features of squamous cell carcinoma.
- Detailed clinical and radiographic findings are described.
Implications:
- This case adds to the limited literature on SCC in OKCs.
- Understanding the diagnostic criteria and treatment of this rare entity is crucial.
- Further research may elucidate the pathogenesis and risk factors for malignant transformation in OKCs.