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Mechanisms of hemopoiesis in athymic mice
V V Zhdanov1, T A Luk'yanova, E V Kirienkova
1Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences.
Bulletin of Experimental Biology and Medicine
|November 7, 2002
Abstract:
Cell elements of peripheral blood and bone marrow and splenic hemopoiesis were studied in athymic BALB/c mice (nude or thymectomized animals). In athymic animals lympho- and erythropoiesis were suppressed, while granulocyto- and monocytopoiesis were activated. These changes were more pronounced in nude mice.