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Ultrastructural peculiarities of intranuclear inclusions in some target cells during endotoxin shock

N G Kharlanova1, Yu M Lomov, E A Bardakhch'yan

  • 1Laboratory of Pathomorphology and Pathophysiology, Plague Control Institute, Rostov-on-Don.

Intranuclear inclusions detected in hepatic, renal, and cerebral cells during endotoxemia can be subdivided into true and pseudo inclusions. True inclusions have filamentous and crystalline structure and are rarely found in control animals. However, the number of true inclusions increases during pathology and can serve as a marker of molecular pathology in the cells provoked by endotoxin.

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