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[Thyroid gland and pregnancy--physiology and pathology]
Katarzyna Łacka1, Hanna Łakoma
1Katedry i Kliniki Endokrynologii i Przemiany Materii Akademii Medycznej w Poznaniu.
Summary
This study details thyroid function changes during pregnancy, covering hormone levels, diagnostic challenges for hyperthyroidism and hypothyroidism, and treatment strategies. It also explores fetal and newborn thyroid health.
Area of Science:
- Endocrinology
- Obstetrics
- Perinatology
Context:
- Pregnancy significantly alters thyroid physiology, impacting both maternal and fetal health.
- Thyroid dysfunction during gestation presents unique diagnostic and therapeutic challenges.
- Accurate assessment of thyroid function is crucial for optimal pregnancy outcomes.
Purpose:
- To comprehensively review thyroid function and structural changes during pregnancy.
- To discuss diagnostic difficulties and modern treatment approaches for thyroid disorders in pregnant women.
- To describe thyroid physiology and pathology in fetuses and newborns.
Summary:
- The review covers alterations in thyroid hormones (TSH, FT4, TT4, TT3, rT3, TBG, Tg) and metabolism during pregnancy.
- It addresses challenges in diagnosing hyperthyroidism and hypothyroidism in pregnant individuals.
- Current treatment strategies and fetal/neonatal thyroid health are also examined.
Impact:
- Provides essential information for clinicians managing thyroid disorders in pregnant patients.
- Highlights the importance of monitoring and treating thyroid dysfunction for maternal-fetal well-being.
- Contributes to a better understanding of thyroid health across the gestational continuum.