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Dam1 is the right one: phosphoregulation of kinetochore biorientation
Andrew M Courtwright1, Xiangwei He
1Department of Biochemistry and Molecular Biology, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston Medical School, 6431 Fannin, 6.200, Houston, TX 77030, USA.
Developmental Cell
|November 15, 2002
Abstract:
Chromosomes have to establish the proper attachment to the spindle before segregation-a process that requires Ipl1p Aurora kinase. Recent work has identified Dam1p, a member of the DASH complex, as the key Ipl1p substrate responsible for kinetochore/microtubule interaction.