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Related Concept Videos

MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...

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Related Experiment Video

Updated: Jul 13, 2026

A Noninvasive Hair Sampling Technique to Obtain High Quality DNA from Elusive Small Mammals
07:40

A Noninvasive Hair Sampling Technique to Obtain High Quality DNA from Elusive Small Mammals

Published on: March 13, 2011

[TrichoScan. A new instrument for digital hair analysis].

R Hoffmann1

  • 1Universitäts-Hautklinik, Marburg, Germany. rolf.hoffman@mailer.uni-marburg.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|November 22, 2002
PubMed
Summary

The TrichoScan method accurately measures hair density, diameter, growth rate, and the anagen/telogen ratio. This tool aids in monitoring hair loss and evaluating treatment effectiveness in clinical dermatology.

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A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
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Last Updated: Jul 13, 2026

A Noninvasive Hair Sampling Technique to Obtain High Quality DNA from Elusive Small Mammals
07:40

A Noninvasive Hair Sampling Technique to Obtain High Quality DNA from Elusive Small Mammals

Published on: March 13, 2011

Flat Mount Imaging of Mouse Skin and Its Application to the Analysis of Hair Follicle Patterning and Sensory Axon Morphology
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A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
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A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

Area of Science:

  • Dermatology and Trichology
  • Medical Imaging and Analysis
  • Biomedical Engineering

Context:

  • Hair loss and thinning are prevalent dermatological concerns.
  • Current methods for assessing hair loss and treatment efficacy are often insensitive.
  • A precise tool is needed to quantify hair growth parameters.

Purpose:

  • To introduce the TrichoScan, a novel method for in situ hair analysis.
  • To evaluate the TrichoScan's ability to measure key hair growth parameters: density, diameter, growth rate, and anagen/telogen ratio.
  • To demonstrate the TrichoScan's utility in clinical research and practice.

Summary:

  • The TrichoScan combines epiluminescence microscopy with digital image analysis for comprehensive hair assessment.
  • It achieves high intraclass correlation coefficients (approx. 91% within-operator, 97% between-operator).
  • The method successfully detected significant increases in hair counts and thickness after treatments like finasteride and minoxidil.

Impact:

  • Enables sensitive monitoring of hair loss conditions like androgenetic alopecia (AGA).
  • Facilitates robust clinical trials comparing treatments, placebos, or different hair growth stimulants.
  • Can be adapted to study drug or laser effects on hypertrichosis and hirsutism.