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[Detection report on noxious elements in Radix astragli].

Xiaochuan Ye1, Fen Deng, Ming Gu

  • 1Hubei Academy of Traditional Chinese Medicine and Pharmacy, Wuhan 430074.

Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials
|November 28, 2002
PubMed
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This study analyzed heavy metals in Astragali, finding low levels of arsenic, mercury, and cadmium. However, lead content in Astragali and its extracts was high, exceeding safety standards.

Area of Science:

  • Pharmacognosy
  • Environmental Chemistry
  • Analytical Chemistry

Background:

  • Astragali is a traditional medicinal herb.
  • Heavy metal contamination is a concern in herbal medicines.

Purpose of the Study:

  • To determine the content and dissolution rates of arsenic (As), mercury (Hg), cadmium (Cd), and lead (Pb) in Astragali samples.
  • To assess the safety of Astragali based on heavy metal levels.

Main Methods:

  • Hydride generation-atomic fluorescence spectrometry (HG-AFS) for As.
  • Cold vapor-atomic absorption spectrometry (CV-ASS) for Hg.
  • Inductively coupled plasma-atomic emission spectrometry (ICP-ES) for Cd and Pb.

Main Results:

  • As content ranged from 0.018-0.617 µg/g, Hg from 0.004-0.181 µg/g, Cd from 0.029-0.168 µg/g, and Pb from 0.290-5.501 µg/g.

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  • Dissolution rates were: As 30.2%-54.2%, Hg 4.9%-9.8%, Cd 50%-87.9%, and Pb 12.6%-27.8%.

    • Conclusions:

    • Arsenic, mercury, and cadmium levels in Astragali were below national food and hygiene standards.
    • Lead content in Astragali and its extracts was high and exceeded safety limits.