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Role of Fig2p in agglutination in Saccharomyces cerevisiae
1Department of Biological Sciences and the Center for Gene Structure and Function, Hunter College, City University of New York, New York 10021, USA.
Eukaryotic Cell
|November 29, 2002
Abstract:
In W303-derived strains, disruption of FIG2 increased agglutinability of alpha cells, but not a cells, and did not alter expression of alpha-agglutinin, binding of 125I-labeled alpha-agglutinin, or mating efficiency. Fig2p overexpression led to alpha-cell-specfic suppression of agglutinability. These results imply that Fig2p is an indirect masker of the active sites in alpha-agglutinin.