Related Experiment Video
Updated: Aug 14, 2026

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
Published on: June 20, 2014
A model of myocarditis
1Department of Physiology, Russian State Medical University, Moscow.
Abstract:
Myocarditis was induced by synergic interactions of serotonin- and cholinergic nerve fibers during potentiation of vagal inhibition of cardiac activity by stimulation of the stellate ganglion. Thus modeled myocarditis was associated with increased content of serotonin and decreased concentrations of acetylcholine and catecholamines in the myocardial tissue. Blockade of 5HT3(S3) receptors in autonomic ganglia and 5HT1,2(S1,2) receptors in the myocardium improved myocardial contractility and reduced the severity of myocarditis.
Related Concept Videos
Myocarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis III: Medical Management
Cardiomyopathy I: Introduction and Classification
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy

