Related Experiment Video
Updated: Sep 28, 2026

Normothermic Machine Perfusion of Rat Kidneys for Transplantation
Published on: January 27, 2026
[Postoperative course after open nephrectomy for organ donation]
Marc-Olivier Bitker1, Benoît Barrou, Catherine Mouquet
1Unité de Transplantation Rénale et Pancréatique, Service d'Urologie, GH Pitié-Salpêtrière, 83, Boulevard de l'Hôpital, 75013 Paris. mo.bitker@psl.ap-hop-paris.fr
Objective:
To evaluate the quality of the postoperative course after conventional organ donation nephrectomy.
Patients And Methods:
Over the last 29 months, 29 organ donation nephrectomies were performed in our hospital. Thirteen donors were non-residents. This series consisted of twenty organ donations between siblings, two organ donations from children to parents and seven organ donations from parents to children. The mean age of the donors was 42 years (range: 21 to 53). Ten pairs were HLA identical, 18 were semi-identical and one pair had only one A identity in common. The mean plasma creatinine on admission was 81 +/- 23 mumol/l.
Results:
Twenty three left kidneys and 3 right kidneys were harvested, with the last two right kidneys removed via a right anterior subcostal incision. Among the 23 left lumbotomies, the 11th rib was preserved in 21 cases in order to decrease postoperative pain. The mean operating time for patients operated by lumbotomy was 90 +/- 11 minutes. The mean postoperative stay (MPS) was 4.56 days (range: 3 to 8 days). The mean morphine consumption during hospitalisation was 40 mg per patient (range: 0 to 105 mg). Only one complication was observed: pneumothorax requiring postoperative drainage for 48 hours with no subsequent sequelae. No donor was transfused intraoperatively or postoperatively and no wound sequelae were observed. The mean plasma creatinine on discharge was 113 +/- 23 mumol/l.
Conclusion:
These results in terms of analgesic consumption, complications, and mean postoperative stay appear to compare favourably with those obtained by other teams, particularly when organ harvesting is performed laparoscopically (MPS: 4.5 days vs 3 days).
Insights
Organ donation nephrectomy shows a favorable postoperative course with low complications and short hospital stays. This study highlights the safety and efficiency of conventional nephrectomy for organ donors.
Area of Science:
- Nephrology
- Transplantation Surgery
- Organ Donation
Context:
- Conventional organ donation nephrectomy is a critical procedure for deceased donors.
- Evaluating postoperative outcomes is essential for donor safety and optimizing resource allocation.
- Understanding the donor's recovery trajectory informs best practices in organ procurement.
Purpose:
- To assess the quality of the postoperative recovery following conventional organ donation nephrectomy.
- To analyze complications, pain management, and length of hospital stay in organ donors.
- To establish benchmarks for postoperative care in organ donation nephrectomy.
Summary:
- A 29-month study of 29 organ donation nephrectomies revealed a mean postoperative stay of 4.56 days.
- Minimal complications (one pneumothorax) and low analgesic consumption (40 mg morphine) were observed.
- No transfusions or wound complications occurred, with creatinine levels returning to near baseline.
Impact:
- The findings suggest conventional nephrectomy offers a favorable postoperative course comparable to laparoscopic techniques.
- This data supports the safety and efficacy of organ donation nephrectomy, potentially encouraging more participation.
- The study provides valuable insights for surgical teams managing organ donors and refining postoperative care protocols.
Related Concept Videos
Kidney Transplant II: Surgical Procedure
Kidney Transplant III: Nursing Management
Kidney Transplant I: Introduction
Peripheral Artery Disease V: Postoperative Nursing Management

