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Tractable Mammalian Cell Infections with Protozoan-primed Bacteria
Published on: April 2, 2013
Severe Legionella pneumophila pneumonia in a patient with iron overload
Holenarasipur R Vikram1, Frank J Bia
1Department of Medicine, Section of Infectious Diseases, Hospital of St. Raphael, Yale University School of Medicine, New Haven, Connecticut 06511, USA. hvikram@srhs.org
Abstract:
Iron plays a crucial role in the energy metabolism of microorganisms. Humans have developed iron-withholding mechanisms as a form of non-specific immunity. We describe a patient with iron overload and severe Legionella pneumophila pneumonia. This report emphasizes the importance of early consideration of and appropriate therapy against Legionella for patients with iron overload who present with community-acquired pneumonia.
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