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Atypical form of active melorheostosis and its treatment with bisphosphonate
Judit Donáth1, Gyula Poór, Csaba Kiss
1National Institute of Rheumatology and Physiotherapy, 1027 Budapest, Hungary. orfireum@matavnet.hu
Skeletal Radiology
|December 17, 2002
Abstract:
We present the case of a 38-year-old man in whom extensive bilateral melorheostosis was associated with elevated serum alkaline phosphatase, swelling of the right foot and progressive deformity of the left hand, left leg and right foot. Radiography, computed tomography and bone scintigraphy were performed. Following treatment with bisphosphonate (30 mg/day of pamidronate for 6 days) infusion, the pain and swelling of his right foot showed improvement and his elevated serum alkaline phosphatase decreased.